Protein-Protein CAPPIA
HTS of protein-protein interactions in mammalian cells using transfected cell arrays
Introduction
Investigation of protein-protein interactions (PPI) within cells is essential for the elucidation of biological processes and cellular networks.
The two-hybrid system is the most commonly used method for PPI analysis.
A high-throughput, cost effective method for analysing PPI directly in mammalian cells was established: the cell array-based protein-protein interaction assay (CAPPIA).
Related application note
HTS of protein-protein interactions in mammalian cells using transfected cell arrays
Related article
High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays.
