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Biochemical Precision Dispensers

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Picoliter to nanoliter non-contact dispensing, from R&D to production-scale manufacturing.

Whether you are developing a diagnostic test, manufacturing biochips or biosensors, or scaling a lateral flow assay to production, SCIENION precision microdispensing platforms deliver accurate, reproducible, non-contact deposition of biomolecules from 10 pL to 5,000 nL, at every scale from R&D to high-throughput manufacturing.
The sciFLEXARRAYER family covers the full range from research-scale to ultra high-throughput production, with standard system configurations ready to deploy and custom-engineered solutions for workflows that go beyond the catalog. All models share the same piezo-driven, non-contact dispensing technology, ensuring consistent performance and reproducibility across scales.
PRODUCT HIGHLIGHTS
droplet

Non-contact liquid dispensing

aim

Ultra-high position precision

drop-ruler

Ultra-high volume accuracy

2droplets

All liquids, including high viscosity

efficacy

Highly customizable and scalable

efficiency-gauge

Minimal dead volume

A modular platform, built to grow with your workflow

From liquid handling channels and dispense heads to environmental control, substrate handling and production-ready software packages, dozens of optional hardware and software extensions can be configured to match your application, throughput and regulatory requirements.
BENEFITS
droplets
Piezo-driven, non-contact microdispensing developed and refined since 2001, validated by hundreds of installations and publications worldwide. We dispense what others cannot.
WHICH SCI FLEXARRAYER SHOULD I CHOOSE?
KEY COMPONENTS
1

HEAD CAMERA FOR POSITION CONTROL AND QUALITY VERIFICATION OF TARGETS AFTER SPOTTING

2

HIGH-PRECISION, HIGH-SPEED XYZ DRIVES

3

TARGET DECK WITH STANDARD OR VACUUM TARGET HOLDERS, UP TO 27 MICROTITRE PLATES PER BATCH ON STANDARD SYSTEMS

4

DROP CAMERA FOR AUTOMATIC DETECTION AND CONTROL OF DROP GENERATION AND DROP VOLUME

5

UP TO 8 DISPENSING CAPILLARIES WITH INDIVIDUAL CONTROLS ON STANDARD SYSTEMS. NO UPPER LIMIT FOR CUSTOM MANUFACTURING BUILDS.

6

SOFTWARE-CONTROLLED RUN AUTOMATION WITH LIVE VISUAL MONITORING OF DROPLET GENERATION AND STABILITY

SCIFLEXARRAYER TECHNOLOGY EXPLAINED

NON-CONTACT DISPENSING

Unlike traditional contact spotting methods, non-contact dispensing delivers precise droplets without ever touching the substrate. This eliminates mechanical stress, prevents contamination, and enables accurate deposition into even the smallest cavities. 

sciFLEXARRAYERs all offer:

  • Vision-controlled precision – Drop volume continuously monitored and adjusted through a proprietary vision-based algorithm.
  • Surface protection – No damage to sensitive substrates.
  • Homogeneous spot morphology – Consistent spot quality across arrays.
  • Miniaturization – Enables dispensing into micro- and nano-scale cavities.

SCIENION offers two different non-contact dispensing technologies: sciDROP PICO and sciDROP NANO which can be used on all sciFLEXARRAYER devices.

SCIDROP PICO

Built on piezo-driven pulses applied to inert glass capillaries, sciDROP PICO ensures gentle and reliable liquid handling across a wide range of applications, from assay development to cell dispensing. Multiple capillary types (PDC60, -70, -80, -90, -100) cover different volume ranges, while tailored surface coatings optimize performance for specific liquid properties. 

It ensures:

  • Unrivaled precision – exact drop volume control with integrated visual detection
  • Gentle handling – no shear stress, preserving sample integrity
  • No satellite droplets – complete control of ejection parameters
  • No additives needed – glycerol-free operation avoids interfering substances
  • Low dead volume – maximal use of precious samples

sciDROP PICO is compatible with all sciFLEXARRAYER scales.

SCIDROP NANO

Built on electromagnetic micro-valve technology, sciDROP NANO bridges the gap between nanoliter and microliter dispensing. It offers robust performance across a wide range of liquid types, from aqueous buffers to viscous or low-surface-tension solutions, making it ideal for bulk spotting and high-throughput applications. Ceramic tips ensure long-term stability and reproducibility. 

It delivers:

  • Flexible volumes – from 50 nL to 5 µL per drop
  • Broad liquid compatibility – handles challenging viscosities and solvents
  • Consistent accuracy – CV typically < 2%
  • Versatile modes – spot-on-the-fly, line printing, predefined patterns
 sciDROP PICOsciDROP NANO
VOLUME RANGE
10 – 800 pL / drop
50 – 5,000 nL / jet
DROP
GENERATION
TECHNOLOGY
Piezoelectrically driven pulses
via an inert (low-reaction) glass capillary (Piezo dispense
capillary, PDC)
Motor driven pump and electromagnetic micro-valve or other valve systems
DISPENSING SOURCE
Aspiration / dispense
Aspiration / dispense
DISPENSING MODE
Stop-and-spot, line printing, and predefined patterns
Stop-and spot, line printing, and predefined patterns
VOLUME ACCURACY
(COEFFICIENT OF
VARIATION)
Typically < 0.5 %
Typically < 2 %
POSITION PRECISION
< 5 µm
< 5 µm
CONSUMABLES
Piezo Dispense Capillaries;
coatable
Ceramic Tips