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Microneedles Are Transforming Drug Delivery

The stratum corneum, just 20 µm thick, represents one of medicine’s most formidable barriers. Microneedles solve this challenge, creating painless pathways through the skin’s outer layer to deliver vaccines, biologics, and small molecules directly into the vascularized dermis and epidermis. With up to 95% pain reduction compared to hypodermic injections and the convenience of self-administration, microneedle patches are transforming drug delivery for everything from insulin and immunotherapy to cosmetic applications.

MICRONEEDLE APPLICATIONS
Microneedles

MICRONEEDLE DRUG COATING

Achieve uniform drug coating or polymer encapsulation for vaccines, biologics or controlled-release therapeutics. sciFLEXARRAYERs dispense in the picoliter volume range for solid microneedle coatings or dissolving polymer matrices, ensuring reproducible dosing and predictable dissolution kinetics essential for regulatory approval and clinical translation.

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HOLLOW MICRONEEDLE RESERVOIRS

Enable sterile, contamination-free filling of hollow microneedle reservoirs for biologics and high-value formulations. Non-contact piezo dispensing eliminates dead volume and ensures dose accuracy from prototyping through GMP manufacturing, supporting continuous infusion or on-demand dosing.

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BIOSENSING & THERANOSTIC PLATFORMS

Deposit biosensing reagents with precision onto microneedle-integrated diagnostic and theranostic platforms. sciFLEXARRAYER enables enzyme, antibody, or nanoparticle layer patterning for continuous glucose monitoring, biomarker detection, and closed-loop drug delivery systems that respond in real time to physiological signals.

The challenge: Ensuring precise, reliable drug loading in complex microneedle structures

Microneedle patch manufacturing requires highly accurate deposition of small volumes onto complex 3D geometries while maintaining precise dose delivery. Challenges include handling formulations with varying viscosity and stability, optimizing surface coatings to balance liquid spreading and confinement, and ensuring scalable, reproducible production processes.
The solution: Non-contact microdispensing with the sciFLEXARRAYER platform
SCIENION-Purple-6
Non-contact piezo dispensing systems enables highly accurate reagent deposition in the ultra-low volume range, delivering consistent droplet volumes and precise drug loading onto complex microneedle structures.