Gentle, Image-Based Sorting and Isolation of 3D Cell Models for Smarter Drug Discovery
spheroONE is redefining how 3D cellular models are prepared and used in drug discovery. Its gentle sorting reduces manual handling and ensures every assay starts with homogenous spheroids or organoids. By transforming variability into consistency, spheroONE enhances data quality, accelerates timelines, and de-risks critical preclinical decisions.
spheroONE ensures consistent and functional 3D models by combining precise image-based isolation with gentle dispensing, based on user-defined parameters. It minimizes variability, preserves fragile structures, and adapts seamlessly across spheroids, organoids, and patient-derived models. With integrated brightfield and fluorescence imaging, it enables sorting based on morphology or phenotypic response. High speed and automation further reduce hands-on time, letting researchers generate reliable, reproducible data at scale with minimal manual intervention.
Over 90% single-oid accuracy ensures every well, every experiment and every lab works with consistent models, reducing false positives and negatives and de-risking critical decisions in drug development pipelines.
Brightfield and multi-channel fluorescence imaging sort 3D models by size, morphology or marker expression, including post-treatment sorting to study phenotypic response and the molecular basis of resistance versus sensitivity.
Image-based selection and gentle dispensing avoid the shear stress and variability of conventional methods, maintaining viability for intact, functional spheroids and organoids.
From spheroids and organoids to patient-derived tumoroids and hydrogel-embedded structures, precision positioning places models into specific wells or substrates for imaging, co-culture and functional assays.
384 spheroids processed in an average of 30 minutes, maintaining over 90% accuracy and viability, with minimal hands-on time once a run is started.
KEY COMPONENTS
1
AUTOMATED SAMPLE MANAGEMENT AND CLEANING
2
FLAT-SECTION CAPILLARY FOR OPTIMAL IMAGING
3
EMBED DIRECTLY IN EXTRACELLULAR MATRIX OF YOUR CHOICE
4
ON-DECK TEMPERATURE CONTROL (4-65°C)
5
PRECISION POSITIONING AXES
RELATED PRODUCTS
cellenONE X1 NEO
All-in-one platform combining high-accuracy single cell isolation and high-precision pico to nanoliter reagent dispensing
