Enhancing the efficiency and reproducibility of Human Pluripotent Stem Cells (hPSC) clonal expansion through gentle Single Cell Isolation and biologically-relevant growth matrices.
Human pluripotent stem cells (hPSCs) are invaluable tools for a wide range of applications, including disease modeling, developmental studies, drug discovery, and emerging cell-based therapies. These cells have the unique ability to differentiate into any cell type, making them essential for understanding fundamental biological processes and developing new therapeutic strategies. However, workflows that require clonal […]
Designing for Discovery: The Technical Foundations of Single-Cell Omics
Single-cell technologies have revolutionized biological research, transitioning from experimental novelty to essential methodology in less than a decade. Exemplifying this, researchers at the Broad Institute used single-cell RNA sequencing to analyze over 500,000 cells across 24 human tissues, creating an unprecedented atlas of human cell types that revealed dozens of previously uncharacterized cell populations [1]. […]
Precision Liquid Dispensing: The Key to Faster, Scalable Diagnostic Development
The need for rapid, reliable, and scalable diagnostic tests has never been greater, whether it’s for addressing challenges with SARS-CoV-2 infections or detecting sexually transmitted diseases like HIV and other pathogens. To meet these needs, manufacturers are turning to precision liquid microdispensing technology, which enables miniaturization of multiplex assays, exceptional accuracy, and scalable high-throughput production. This innovation […]
High-Throughput vs. High-Accuracy in Single-Cell Omics
Technological advancements have significantly enhanced our investigations into biological systems. At the forefront of these innovations are single-cell omics, an ensemble of technologies that facilitate the analysis of the molecular components within individual cells, i.e., single-cell sequencing of genomes (single cell genomics, or scWGS), transcriptomes (single cell transcriptomics, or scRNA-seq), proteomes (single cell proteomics, or […]
Mastering Single-Cell Sequencing: Key Choices in Library Prep & Why They Matter
Single-cell sequencing enables researchers to study cellular diversity, unlocking critical insights into fields like oncology, neurology, and immunology. By analyzing individual cells, researchers can detect rare mutations, track disease progression, and understand cellular heterogeneity with unprecedented precision. However, success in single-cell sequencing depends on the quality of cell isolation and Next-Generation Sequencing (NGS) library preparation. This blog explores how […]
How Picoliter Dispensing is Transforming Scientific Research and Innovation
In modern research, precision is everything. As scientists push the boundaries of innovation, picoliter dispensing has become an important tool, enabling ultra-miniaturized assays, reducing reagent waste, and enhancing experimental accuracy. Whether in biotech, diagnostics, or materials science, this technology brings speed without compromising quality and savings without reducing research output. From high-density biochips to biosensors, Microdispensing is enhancing workflows […]
Uncovering the Origins of Breast Cancer: Insights from Healthy Cells Powered by Single Cell Genomics
Breast cancer is the most common cancer among women worldwide, with an estimated 2.3 million new cases diagnosed in 2024 alone. In the United States, approximately 1 in 8 women will develop breast cancer in their lifetime. Early detection and advances in treatment have significantly improved survival rates, with a 5-year relative survival rate of […]
From individual microbial cells to microbial dark matter with single microbial cell approaches
The holobiont paradigm finally acknowledges that the development and health of macroorganisms, as all other natural ecosystems, are shaped by the complex microbial communities they host. Yet, mechanistic insights into microbial community assembly and their interactions with their environment are still scarce. While it is currently estimated that less than 1% of prokaryotic species can […]
Accelerating Progress in Breast Cancer Diagnostics using Precision Microdispensing
Breast cancer is one of the most prevalent and concerning diseases affecting women worldwide. A lot of ongoing research focuses on the development of breast cancer diagnostics to identify and characterize breast tumors, enabling healthcare professionals to determine the stage and type of cancer, as well as to guide treatment decisions. In this blog post, […]
Microneedles – tiny devices with huge potential in drug delivery and POC diagnostics
Microneedles have the potential to revolutionize the healthcare industry in drug delivery and diagnostics. These microscopic needles, too small to be seen by the naked eye, have been designed to deliver drugs through the skin without causing pain. Compared to traditional methods like injections or oral medication, microneedles offer a range of benefits. They are […]