Cellenion present here solutions for single-cell analyses of 3D cellular models. Cellenion has developed cellenONE, a unique system able to both isolate single-cell with high accuracy and dispense nanoliters of reagents allowing miniaturization of sample preparation for OMICs studies. The emergence of single-cell analyses has revolutionized Biology most notably in the field of Oncology. Making single-cell analyses affordable is critical to the deployment of these methods to other research fields.
In this webinar, Dr Segolene Ferratge presents results from a comparative transcriptomic study on HepaRG™ cells grown in traditional 2D monolayer versus 3D spheroids. This study demonstrates the power of single-cell analyses and confirms that HepaRG™ cells grown as 3D spheroids show a more hepatic phenotype as compared to cells cultured in a 2D monolayer.