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cellen ONE X1 Neo

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cellenONE X1 NEO, the turn-key solution for single cell omics workflows: get the Material, the Methods and the Know-How!

NEO is the optimal tool for the preparation of single cell omics samples, thanks to end-to-end automated workflows and optimized environmental controls allowing on-deck incubations. And because it shares the core technologies of all cellenONE single cell dispensers, it is virtually compatible with any other single cell applications.

Trusted by leading institutions

R&D

Single cell isolation

dispensing

Precision liquid dispensing

temp

On-deck temperature control

Group 1924

Brightfield and/or Fluorescence

multimedia

Image recording of every isolated cell

Contract

End-to-end sample preparation workflows

Benefits

Adjust your instrument to your needs, by adding one or several of our application-dedicated packages: these contain all hardware and software options optimized for your workflows, from cell line development to multiplexed and label free single cell proteomics. Together with this Material & Methods, you receive training from our expert scientiststhat transfer their know-how, so you are quickly set to go! 

cellenONE NEO introduces advanced environmental controls, including precise temperature and humidity regulation. It ensures optimal conditions for sensitive cell handling, molecular biology reagent safeguarding, and direct incubations of reactions on the printing deck.  

Need streamlined single cell proteomics workflow with minimal hands-on time and maximal proteome coverage? The combination of cellenONE NEO and Cellenion proteoCHIP product range provides robust automated method for single cell proteomics sample preparation. Feed the system with your cell sample, let it guide you through your workflow and output your sample ready for LC-MS. 

While the NEO introduces powerful new features, it remainsfirst and foremost, a true cellenONEoffering precise cell and reagent dispensing, up to 100% live single-cell accuracy, customizable sorting parameters, fast startup, flexible multi-sample-to-multi-target workflows, and long-term durability built for sustainable use. 

Key Features
1

UP TO 8 DISPENSING CAPILLARIES WITH INDIVIDUAL CONTROLS

2

High precision and high speed XYZ spindle drives

3

Head camera for position control and QC of targets after spotting

4

UP to 36 STANDARD MICROSCOPE slides or 4 MTP PER RUN

5

TARGET DECK, WITH STANDARD, or VACCUUM TARGET HOLDER

6

PC CONTROL WITH FLEXIBE RUN AUTOMATION AND LIVE VISUAL CONTROL OF DROPLET STABILITY

Precision microdispensing applications

Microneedles

Dispensing vaccines, drugs, or diagnostics onto microneedle patches with high precision for minimally invasive delivery platforms.

point-of-care

Develop point-of-care testing devices that provide immediate results, improving patient outcomes through timely diagnosis.

microarray & biosensors

Enabling multiplexed diagnostics with precise spotting of DNA, proteins, or other biomolecules on diverse surfaces.

microfluidics

Filling microhannels, chambers, and lab-on-chip systems with accuracy and repeatability for diagnostics and research workflows. 

lateral flow

Automating reagent spotting onto lateral flow assays with consistency and accuracy, from development to large-scale manufacturing

Other applications

Discover flexible solutions for novel formats and challenging substrates across diagnostics, life science, and industrial applications.

Case Study

PLASMONIC MICROARRAYS FOR NEURODEGENERATIVE RESEARCH WITH SCI FLEXARRAYER S3

The Challenge

Quantifying protein structural changes in drug screening.

EPFL researchers set out to create a labelfree method to study how drugs affect protein aggregation in neurodegenerative diseases. Conventional fluorescence and ThT assays could not reliably detect early aggregation states or mixed structural forms of αsynuclein, limiting insight into drug efficacy. The team needed a platform that combined highthroughput screening with nanoscale structural precision.

The Solution

Automated nanoliter spotting for plasmonic IR microarrays

Using the sciFLEXARRAYER S3, droplets of protein drug samples were printed into 48, 96, and 384 well plasmonic sensor chips. Each microwell contained gold nanorod arrays optimized for surface enhanced infrared absorption (SEIRA). The S3’s piezo driven, noncontact dispensing and fiducial control produced highly uniform ~450 pL spots without contamination, vital for infrared precision.

The Outcome

Accelerating label-free biomarker screening in neuroscience.

Published in Advanced Science (2025), the work showed that these
plasmonic microarrays quantify
protein secondary structures in
real-time from as little as 2 nL per
well, with sensitivity down to 100
pg/mL. The arrays offered a new
quantitative tool for screening
neurodegenerative disease therapeutics with unmatched speed and
resolution.

Nanoplasmonic Infrared Microarray Sensor Enabling Structural Protein Biomarker-Based Drug Screening for Neurodegenerative Diseases

Deepthy Kavungal, Enzo Morro, Senthil T Kumar, Berkay Dagli, Hilal A Lashuel, and Hatice Altug.
Advanced Science, 2025

Other products in the sciFLEXARRAYER range

See all sciFLEXARRAYER S3 resources

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