cellenONE single cell dispensers
The cellenONE single cell dispenser range are all-in-one platforms combining high-accuracy single cell isolation and high-precision pico- to nanoliter reagent dispensing.
Combining ultra-precise image-based single‑cell isolation with gentle droplet dispensing, the cellenONE platforms deliver 100% accuracy, exceptional viability, and compatibility with cells sized 0.5–80 µm. They empower breakthroughs in various cutting-edge applications, such as single cell omics, spatial proteomics, cell engineering and high-throughput bioprocessing. Available in multiple versions to fit diverse application needs, from R&D to GMP environments.
Trusted by leading institutions
Single cell isolation
Precision liquid dispensing
On-deck temperature control
Brightfield and/or Fluorescence
Image recording of every isolated cell
End-to-end sample preparation workflows
Benefits
Controlled low-volume aspiration and dispense of any type of reagents or cell solutions empower complete single cell workflows, from cell isolation to miniaturization of sample prep reaction, including single cell proteomics. Increase the sensitivity and reproducibility of your single cell omics analysis, while minimizing reagent costs!
Image-based verification and real-time monitoring ensure true single-cell deposition, eliminating doublets and empty wells for fully reliable single-cell assays. Gentle dispensing ensures minimal stress and exceptional viability, enabling robust clonal outgrowth for sensitive cells, stem cells, and engineered lines across demanding workflows.
You want to target only certain sub-populations? Set custom gating and sorting rules based on cell morphology, fluorescence, or viability, giving you complete control and reproducibility across different cell types or conditions.
Optimized design reduces prep and cleaning time, enabling quick daily operation and higher productivity and simpler processes. From simple task automation to full integration in multi-instrument workcells, cellenONE minimizes hands-on time and increase reproducibility.
Dispense from various samples in the same automated run: the workflow adapts to your needs. Deposit your reagents or cells in any kind of targets, from standard well–plates to microwells consumables, or any custom geometry microchip, thanks to precise spatial positioning: it’s just like 3D printing your cellular assays!
cellenONE is consumable-free: its dispensing capillary is made of glass and easily sterilizable by automated system tasks. The platform comes with service and maintenance, throughout its lifecycle, to guarantee its use in the best possible conditions, long term.
Key Features
DISPEnse cells and reagents with ultra gentle wave
dispense cells in any target consumable
control the temperature and humidity of your sample and targets
select only cells of interest using imaged morphology and fluorescence criteria
ONE PLATFORM, DIFFERENT VERSIONS
Applications
OMICS
CLONING
Single cell genomics
Cell engineering
Single cell transcriptomics
Stem Cells
Single cell epigenetics
Synthetic Biology
Single cell proteomics
Monoclonal antibody
Spatial proteomics
Microbiology
CELLEN ONE TECHNOLOGY EXPLAINED
HIGH PRECISION PICOLITER DISPENSING
The sciDROP PICO is SCIENION’s proprietary ultra low-volume drop-on-demand dispensing technology. It uses non-contact acoustic wave, generated by a piezoelectric element, to generate droplets of controlled and highly reproducible volume, from 250 to 600 pL per drop.
A PERFORMANT OPTICAL SYSTEM
A high-resolution optical system, allows microscopic observations of single cells and monitoring of their size, elongation and fluorescence pattern: DAPI (ex. 375 nm; em. 432 nm), FITC (ex. 470 nm; em. 515 nm), Cy3 (ex. 565 nm; em. 580 nm), Cy5 (ex. 625 nm; em. 670 nm).
ISBCI™ IMAGE-BASED SINGLE CELL ISOLATION
Isolation decision is automated by cellenONE software based on image analysis. When multiple cells (1) or no cells (2) are found in the volume of liquid that will be ejected next, drops are dispensed in a recovery vial. When one, and just one, cell corresponding to user-defined criteria, is detected (3), the capillary is moved to the target position and the drop containing the cell is ejected onto it (4).