Lateral Flow

Lateral Flow

From Rapid Tests to Advanced Diagnostics: Redefining Lateral Flow with SCIENION Precision

Lateral flow is a rapid, simple, and low-cost diagnostic technology widely used for point-of-care testing. It works by allowing a liquid sample to migrate along a membrane strip, where immobilized reagents capture target molecules, producing a visible result typically within minutes. Many are familiar with lateral flow through common applications, such as pregnancy testing and COVID-19 rapid antigen testing. 

Lateral flow is widely used due to its accessibility. Tests are portable, requiring little to no specialized equipment, and can be performed by non-experts, making them easy to use in clinical, home, and field settings. This has driven widespread adoption across healthcare, women’s health, infectious disease testing, veterinary diagnostics, and environmental monitoring. As well as being simple and affordable, lateral flow assays provide results in real-time, supporting fast decision-making.  

Traditionally, lateral flow has been limited to qualitative or semi-quantitative results. However, ongoing innovations are expanding what these platforms can achieve. Multiplexing enables the detection of several analytes in a single test, while microarray integration brings higher sensitivity and more detailed analysis. New membrane technologies are also improving signal strength and reliability, making lateral flow competitive with laboratory-based techniques.  

With precision dispensing technologies such as the sciFLEXARRAYER series and sciDROP PICO technology, SCIENION supports accurate and reproducible reagent deposition at ultra-low volumes, advancing next-generation lateral flow systems. This precision, combined with expertise in microarrays and integration with advanced membranes, allows developers to build more robust, multiplexed assays. By enabling scalable production and innovative designs, SCIENION supports driving lateral low into new applications, from cancer diagnostics to personalized medicine, all while maintaining the speed, simplicity, and affordability that this technology is renowned for.   

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Lateral flow APPLICATIONS

covid

Clinical & Infectious Disease Diagnostics ​

From influenza to COVID-19, precise reagent placement ensures reproducible, sensitive, and scalable diagnostics, supporting rapid, point-of-care decision-making in hospitals, clinics, and at home.
Unisart

Multiplex & Quantitative Lateral Flow

This evolution transforms qualitative strips into quantitative, high-content assays for personalized medicine and advanced disease management.

technology

Food, Environmental & Accessible Diagnostics

With consistent spotting and low-volume reagent use, reliable lateral flow tests are accessible even in low-resource or on-site environments, ensuring global impact and affordability.

Empowering Confidence in Every Test..

SCIENION brings microdispensing accuracy to the heart of global diagnostics. By ensuring consistency, sensitivity, and scalability, we help make rapid testing more reliable and accessible, empowering better health outcomes, everywhere. 

Featured Resources
WEBINAR
Multiplexing with Unisart StructSure® Membranes

Multiplex lateral flow assays can rapidly analyze multiple parameters or biomarkers simultaneously, making them powerful tools for disease management. Sartorius has developed Unisart StructSure® membranes using SCIENION’s sciFLEXARRAYER dot-based dispensing technology to transform conventional line assays into spot-based formats with higher sensitivity, lower background, and improved reliability. This approach supports advanced assay development, cassette integration, and next-generation lateral flow readouts for robust multiplex diagnostics. 

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Publication
sciFLEXARRAYER Accelerates On-Site Marine Toxin Detection

Professor Katrina Campbell’s group at the internationally recognized Institute for Global Food Security (IGFS, Queen’s University Belfast) developed a pioneering multiplex lateral flow assay for rapid, on-site detection of multiple marine toxins in shellfish. The sciFLEXARRAYER S3 enabled ultra-precise, reproducible printing of toxin conjugates onto nitrocellulose membranes, crucial for assay sensitivity, specificity, and regulatory compliance. IGFS is a global hub for innovative food safety biosensors; Campbell’s research leadership and sciFLEXARRAYER technology are propelling SMART diagnostics toward the field and supply-chain impact. 

APPICATION NOTE
Wageningen Uni × SCIENION: Rapid Multi-Analyte Diagnostics, Perfected

At Wageningen University’s esteemed Food & Biobased Research, Dr. Aart van Amerongen’s Biomolecular Sensing & Diagnostics group developed rapid, multiplexed immunoassays for pathogens and biomarkers relevant to agriculture, food, and health. Leveraging the sciFLEXARRAYER for high-precision spotting of proteins, antibodies, and nucleic acids onto both 2D and 3D substrates, including nitrocellulose lateral flow membranes, the team created robust lateral flow tests capable of simultaneously detecting multiple targets in minutes.  

Publication
A Paper-Based Assay for Cervical Precancer Detection

A low-cost sample-to-answer paper-based assay has been developed to detect HPV E7 oncoproteins for cervical precancer screening. The assay uses an enzyme-linked immunoassay (ELISA) with high sensitivity and requires no instrumentation, making it suitable for resource-limited settings. Capture lines were printed onto nitrocellulose membranes using SCIENION’s sciFLEXARRAYER S3, enabling reproducible assay development. This platform shows strong potential for point-of-care women’s health diagnostics. 

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