sciDROP PICO

 

SCIENION’s non-contact proprietary dispensing technology takes microarray spotting to the next level. The technology, as patented by SCIENION, is called sciDROP PICO, and covers dispensing a liquid sample from 50 to 800 pL per drop.

This non-contact technology, introduced in 2009 and in continuous improvement, offers a number of benefits over contact spotting.

  •     Homogenous spot morphology
  •     No damage to sensitive surfaces, as can result from contacting metal pins
  •     Dispensing into very small cavities
  •     Drop volume is fully controlled by implementing a proprietary vision-based algorithm

 

SCIENION’s sciDROP PICO is a state of the art non-contact dispensing technology based on piezo driven pulses on an inert glass capillary.

This enables accurate and precise droplet deposition under various conditions. 

All Piezo Dispense Capillaries (PDCs) aspirate and dispense liquid at the picoliter scale.

The sciDROP PICO option, together with SCIENION´s surface coating technology, provides access to a broad field of applications with high accuracy and precision dispensing a wide range of liquids:

We find the best PDC size and coating combination for your application!

  • Benefits of sciDROP PICO

    • Gentle acoustic dispensing of samples, no shear stress
    • Living cells are successfully dispensed
    • No added glycerol is needed in the system liquid
    • Precise drop volume control with unique visual detection
    • Absolute zero dead volume
    • No crystallization of sample inside the tip due to a round orifice
    • No satellite drops due to full drop ejection parameters control

Slow Motion Drop on Drop using sciDROP PICO technology


  • Technical Information Piezo Dispense Capillary (PDC)

    Piezo dispensing Non-contact
    Capillary orifice 35 - 75 µm
    Spot frequency 200 - 1500 Hz
    Typical spot size 80 - 250 µm
    Average CV of drop volumes <2%, typically < 0.5 %
    Typical pitch (spacing) Freely scalable (> 50 µm)
    Capillary materials Borosilicate glass, TEFLON® tube, PEEK fitting
    Materials (in contact with medium) PEEK, stainless steel, corundum
    Viscosity of spotable media 0.4 - 5 (mPa.s)
  • Piezo Dispense Capillary Sizes & Coatings

    PDC 40 100-150 pl
    PDC 50 150-220 pl
    PDC 60 220-300 pl
    PDC 70 300-360 pl
    PDC 80 360-440 pl
    PDC 90 440-520 pl
    PDC 100 520-600 pl
    PDC 110 600-800 pl
      With coating types
    Type 1 Aqueous solutions and organic solvents
    Type 2 Samples containing organic solvents like DMSO, DMF etc. and protein mixtures (lysates, allergens etc.)
    Type 3 Samples containing protein solutions and organic solvents like methanol, isopropanol, acetonitrile etc.)
    Type 4 Protein solutions and Sol-Gel samples
    Coating special According to customer specifications