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SCIENION’s non-contact proprietary dispensing technology takes microarray spotting to the next level. The technology, as patented by SCIENION, is called sciDROP PICO, and covers dispensing a liquid sample from 10 pL* to 800 pL per drop.
This non-contact technology offers a number of benefits over contact spotting.
In combination with sciDROP NANO, the total volume range between 10 pL and 100 μL is covered by a single sciFLEXARRAYER instrument.
*results obtained with optimized samples and configuration
Thanks to our surface characterization expertise, we have developed inert glass Piezo Dispense Capillaries (PDCs) which can be coated to improve the quality of the dispensed solution. We have worked very successfully with the following solutions but this list is not exhaustive.See list of Dispensable Media
SCIENION’s sciDROP PICO is a state of the art non-contact dispensing technology based on piezo driven pulses on an inert glass capillary.
This enables accurate and precise droplet deposition under various conditions.
All Piezo Dispense Capillaries (PDCs) aspirate and dispense liquid at the picoliter scale.
The sciDROP PICO option, together with SCIENION´s surface coating technology, provides access to a broad field of applications with high accuracy and precision dispensing a wide range of liquids:
We find the best PDC size and coating combination for your application!
Slow Motion Drop on Drop using sciDROP PICO technology
|Capillary orifice||35 - 75 µm|
|Spot frequency||200 - 1500 Hz|
|Typical spot size||80 - 250 µm|
|Average CV of drop volumes||<2%, typically < 0.5 %|
|Typical pitch (spacing)||Freely scalable (> 50 µm)|
|Capillary materials||Borosilicate glass, TEFLON® tube, PEEK fitting|
|Materials (in contact with medium)||PEEK, stainless steel, corundum|
|Viscosity of spotable media||0.4 - 5 (mPa.s)|
|PDC 40||100-150 pl|
|PDC 50||150-220 pl|
|PDC 60||220-300 pl|
|PDC 70||300-360 pl|
|PDC 80||360-440 pl|
|PDC 90||440-520 pl|
|PDC 100||520-600 pl|
|PDC 110||600-800 pl|
|With coating types|
|Type 1||Aqueous solutions and organic solvents|
|Type 2||Samples containing organic solvents like DMSO, DMF etc. and protein mixtures (lysates, allergens etc.)|
|Type 3||Samples containing protein solutions and organic solvents like methanol, isopropanol, acetonitrile etc.)|
|Type 4||Protein solutions and Sol-Gel samples|
|Coating special||According to customer specifications|