Generated by Rank Math SEO, this is an llms.txt file designed to help LLMs better understand and index this website. # SCIENION: Global Leader in Precision Dispensing ## Sitemaps [XML Sitemap](https://www.scienion.com/sitemap_index.xml): Includes all crawlable and indexable pages. ## Posts - [Breaking Barriers: Handling Challenging Surfaces with Microdispensing Technology](https://www.scienion.com/breaking-barriers-handling-challenging-surfaces-with-microdispensing-technology/): Many application scientists using microdispensing tools know the frustration: after investing in advanced dispensing technology and weeks of optimizing their protocols, they still experience unreproducible dispensing. The first assumption is that the instrument has reached its limits. - [From URS to Validated Production: Why Most Custom Automation Projects Fail](https://www.scienion.com/from-urs-to-validated-production-why-most-custom-automation-projects-fail/): After 25 years of building custom precision microdispensing systems for diagnostics and life sciences manufacturers, we have seen enough of them to know where to look. Every custom automation project typically passes through the same sequence of phases: the diagram below traces that journey (Fig. 1). Each of the four failure points described in this article maps to a specific stage in this sequence, from the first requirements conversations to validated production. - [Designing a Validation-Ready Precision Dispensing Workstation: What Regulated Industries Need To Get Right](https://www.scienion.com/validation-ready-precision-dispensing-workstation/): Good Manufacturing Practice (GMP) and related validation guidelines form the backbone of regulated industries such as pharmaceuticals or In Vitro Diagnostics (IVD). They establish global standards to ensure that products are consistently developed and manufactured safely, effectively, and of high quality. - [Meet the Experts: Thomas & Simon | From Customer Requirements to Validated Custom Systems ](https://www.scienion.com/meet-the-experts-thomas-simon-from-customer-requirements-to-validated-custom-systems/): Behind every custom solution at SCIENION stands a structured engineering process, from User Requirement Specification (URS) to acceptance tests.   - [Meet the Experts: Talena – Empowering Customer Success Through Teamwork](https://www.scienion.com/meet-the-experts-talena-empowering-customer-success-through-teamwork/): As the Team Lead of Commercial Applications in Berlin, my team and I serve as the primary technical contact for our customers. We work closely with them to understand their needs and demonstrate how our technology can help them achieve their goals. Through technical demonstrations, Proof-of-Principle studies, and hands-on training, we help our customers develop deep expertise with our products and support them in turning their ideas into real solutions.  - [How Precision Microdispensing Accelerates Adaptyx’s Wearable Biosensor Development](https://www.scienion.com/how-precision-microdispensing-accelerates-adaptyxs-wearable-biosensor-development/):   - [Meet the Experts: Svenja on Precision Microdispensing and Assay Development | Women in Science](https://www.scienion.com/meet-the-experts-svenja-plesshoff/): Behind every instrument, assay, and workflow is deep expertise.In Meet the Experts, we introduce the scientists, engineers, and specialists at SCIENION and Cellenion who develop, adapt, and support solutions that make complex workflows robust and reproducible. For more than a decade, Svenja has been working at the interface of R&D and customer applications, developing assays and solutions that translate advanced technology into reliable, customer-ready results. This is her perspective on our company, her job, and Women in Science. - [From Molecules to Meaning: The Promise of Single-Cell Proteomics at IMP Vienna](https://www.scienion.com/from-molecules-to-meaning-the-promise-of-single-cell-proteomics-at-imp-vienna/): Upcoming Conference – 6th European Symposium on Single Cell Proteomics – August 2025 – Vienna (ESCP) - [Microliter, nanoliter or picoliter dispensing: small can be really BIG](https://www.scienion.com/microliter-nanoliter-or-picoliter-dispensing-small-can-be-really-big/): Sure, microliters, nanoliters and picoliters all sound small. But just like an elephant, a koala, and a Etruscan shrew (the smallest mammal in the world), evolution has shown that even small ones can be giants, too! - [Spatial Proteomics: Charting the Protein Landscape in Tissues](https://www.scienion.com/spatial-proteomics-charting-the-protein-landscape-in-tissues/): Understanding the spatial organization of proteins within tissues is crucial for unraveling the complexities of cellular behavior, disease progression, and therapeutic responses. Spatial proteomics bridges the gap left by traditional untargeted bulk analyses, offering unprecedented insights into regulatory networks at cellular and inter-cellular levels. In this blog, we explore the fundamentals of this experimental approach, its challenges, and the single-cell spatial proteomics methods driving it forward. - [Miniaturizing ELISA: How Precision Microdispensing Enables High-Sensitivity, Low-Volume Assays](https://www.scienion.com/miniaturizing-elisa-how-precision-microdispensing-enables-high-sensitivity-low-volume-assays/): Enzyme-linked Immunosorbent Assays (ELISAs) have long been the benchmark for detecting analytes in clinical and research settings. While effective, traditional ELISAs are resource-intensive, time-consuming to perform, and ill-suited for high-throughput, multiplex applications. As scientific workflows demand faster and more cost-efficient solutions, it is clear that the classic format needs a modern upgrade. Miniaturized ELISAs offer a powerful upgrade, leveraging picoliter dispensing to cut costs, accelerate timelines, and scale assays without sacrificing data quality. In this article, we discuss the shortcomings of traditional ELISA and how miniaturization paves the way for faster, scalable, and more efficient assays across diverse applications. - [Enhancing the efficiency and reproducibility of Human Pluripotent Stem Cells (hPSC) clonal expansion through gentle Single Cell Isolation and biologically-relevant growth matrices.](https://www.scienion.com/enhancing-the-efficiency-and-reproducibility-of-human-pluripotent-stem-cells-hpsc-clonal-expansion-through-gentle-single-cell-isolation-and-biologically-relevant-growth-matrices/): Human pluripotent stem cells (hPSCs) are invaluable tools for a wide range of applications, including disease modeling, developmental studies, drug discovery, and emerging cell-based therapies. These cells have the unique ability to differentiate into any cell type, making them essential for understanding fundamental biological processes and developing new therapeutic strategies. However, workflows that require clonal expansion from single cells, such as CRISPR/Cas9-mediated genome editing, face significant challenges in terms of efficiency, cost, and precision. By leveraging advanced technologies combining automated single cell dispensing and optimized growth matrices, researchers can achieve higher quality, and more reliable cell lines, at controlled costs, for various applications.  - [Designing for Discovery: The Technical Foundations of Single-Cell Omics](https://www.scienion.com/designing-for-discovery-the-technical-foundations-of-single-cell-omics/): Single-cell technologies have revolutionized biological research, transitioning from experimental novelty to essential methodology in less than a decade. Exemplifying this, researchers at the Broad Institute used single-cell RNA sequencing to analyze over 500,000 cells across 24 human tissues, creating an unprecedented atlas of human cell types that revealed dozens of previously uncharacterized cell populations .   - [Precision Liquid Dispensing: The Key to Faster, Scalable Diagnostic Development](https://www.scienion.com/precision-liquid-dispensing-the-key-to-faster-scalable-diagnostic-development/): The need for rapid, reliable, and scalable diagnostic tests has never been greater, whether it’s for addressing challenges with SARS-CoV-2 infections or detecting sexually transmitted diseases like HIV and other pathogens. To meet these needs, manufacturers are turning to precision liquid microdispensing technology, which enables miniaturization of multiplex assays, exceptional accuracy, and scalable high-throughput production. This innovation is transforming diagnostic manufacturing by improving efficiency, reducing waste, and ensuring consistent test performance. In this article, we explore how precision microdispensing is shaping the future of diagnostics, making advanced healthcare solutions more accessible, cost-effective, and impactful worldwide. - [High-Throughput vs. High-Accuracy in Single-Cell Omics](https://www.scienion.com/high-throughput-vs-high-accuracy-in-single-cell-omics/): Technological advancements have significantly enhanced our investigations into biological systems. At the forefront of these innovations are single-cell omics, an ensemble of technologies that facilitate the analysis of the molecular components within individual cells, i.e., single-cell sequencing of genomes (single cell genomics, or scWGS), transcriptomes (single cell transcriptomics, or scRNA-seq), proteomes (single cell proteomics, or SCP), and other types of molecules for single cell metabolomics. They enable scientists to examine individual cells and cell heterogeneity with unprecedented detail. - [Mastering Single-Cell Sequencing: Key Choices in Library Prep & Why They Matter](https://www.scienion.com/mastering-single-cell-sequencing-from-library-preparation-to-sequencing/): Single-cell sequencing enables researchers to study cellular diversity, unlocking critical insights into fields like oncology, neurology, and immunology. By analyzing individual cells, researchers can detect rare mutations, track disease progression, and understand cellular heterogeneity with unprecedented precision. However, success in single-cell sequencing depends on the quality of cell isolation and Next-Generation Sequencing (NGS) library preparation. This blog explores how cutting-edge single cell isolation and precision dispensing technologies enhance sequencing accuracy, reduces reagent waste, and streamlines workflows, driving the next generation of single-cell genomic discoveries. - [How Picoliter Dispensing is Transforming Scientific Research and Innovation](https://www.scienion.com/how-picoliter-dispensing-is-transforming-scientific-research-and-innovation/): In modern research, precision is everything. As scientists push the boundaries of innovation, picoliter dispensing has become an important tool, enabling ultra-miniaturized assays, reducing reagent waste, and enhancing experimental accuracy. Whether in biotech, diagnostics, or materials science, this technology brings speed without compromising quality and savings without reducing research output. From high-density biochips to biosensors, Microdispensing is enhancing workflows and empowering researchers to make groundbreaking discoveries. - [Uncovering the Origins of Breast Cancer: Insights from Healthy Cells Powered by Single Cell Genomics](https://www.scienion.com/uncovering-the-origins-of-breast-cancer-insights-from-healthy-cells/): Breast cancer is the most common cancer among women worldwide, with an estimated 2.3 million new cases diagnosed in 2024 alone. In the United States, approximately 1 in 8 women will develop breast cancer in their lifetime. Early detection and advances in treatment have significantly improved survival rates, with a 5-year relative survival rate of 99% for localized breast cancer. However, breast cancer remains the second leading cause of cancer death among women, underscoring the need for continued research and innovation in this field. Single-cell sequencing, i.e., mainly single cell genomics and single cell transcriptomics have revolutionized cancer research by enabling detailed analyses of individual cells.   - [From individual microbial cells to microbial dark matter with single microbial cell approaches](https://www.scienion.com/from-individual-microbial-cells-to-microbial-dark-matter-with-single-microbial-cell-approaches/): The holobiont paradigm finally acknowledges that the development and health of macroorganisms, as all other natural ecosystems, are shaped by the complex microbial communities they host. Yet, mechanistic insights into microbial community assembly and their interactions with their environment are still scarce. While it is currently estimated that less than 1% of prokaryotic species can be cultivated in the lab, meta-omics (especially metagenomics) have been the top microbiology methods over the past 2 decades. They allowed a significant number of high-impact discoveries, but they also raised an even more significant number of questions. Be it for fundamental research purposes or with a view to provide reasoned solutions, there is now a need for stepping back from empirical approaches and gaining knowledge of the mechanisms underlying the observed patterns . - [Accelerating Progress in Breast Cancer Diagnostics using Precision Microdispensing](https://www.scienion.com/accelerating-progress-in-breast-cancer-diagnostics-using-precision-microdispensing/): Breast cancer is one of the most prevalent and concerning diseases affecting women worldwide. A lot of ongoing research focuses on the development of breast cancer diagnostics to identify and characterize breast tumors, enabling healthcare professionals to determine the stage and type of cancer, as well as to guide treatment decisions. - [Microneedles – tiny devices with huge potential in drug delivery and POC diagnostics](https://www.scienion.com/microneedles-tiny-devices-with-huge-potential-in-drug-delivery-and-poc-diagnostics/): Microneedles have the potential to revolutionize the healthcare industry in drug delivery and diagnostics. These microscopic needles, too small to be seen by the naked eye, have been designed to deliver drugs through the skin without causing pain. Compared to traditional methods like injections or oral medication, microneedles offer a range of benefits. They are minimally invasive, and can even be used to detect clinically significant substances through the skin. This blog post will delve into the world of microneedles, exploring their potential, benefits, applications, and challenges, and how they are poised to revolutionize drug delivery and diagnostics. - [Parallel detection and differentiation of respiratory viruses](https://www.scienion.com/parallel-detection-and-differentiation-of-respiratory-viruses/): The COVID-19 outbreak created urgency for innovative diagnostic technologies. The triple-demic of COVID-19, RSV and influenza brought new challenges. ## Pages - [Report a Security Incident](https://www.scienion.com/report-a-cyber-security-incident/): Contact the BICO Security team to report a suspected security incident so that we can immediately trigger the incident response activities and limit the incident’s business impact. - [Order consumables](https://www.scienion.com/customer-service/order-consumables/): Order Consumables Get a Quote for Consumables - [sciFLEXARRAYER | Precision Microdispensers for Diagnostics and Life Sciences](https://www.scienion.com/precision-microdispensers-sciflexarrayer/): sciFLEXARRAYER is a range of high-precision, non-contact dispensing systems designed for the accurate spotting of liquids from 10 pL to 5,000 nL.  - [Contact](https://www.scienion.com/customer-service/contact/): Customer Service Contact Support - [Certificates](https://www.scienion.com/certificates/): ISO 9001:2015 Certificate - EN - [Blog](https://www.scienion.com/resource-hub/blog/): We regularly update our blog to reflect the latest developments, emerging trends, and ongoing conversations in the ever-evolving world of science, particularly those that intersect with our technology and areas of expertise.  - [Application and Technical Notes](https://www.scienion.com/resource-hub/application-notes/): Gain a comprehensive understanding of the full capabilities of our advanced technologies, including the wide range of scientific applications and workflows they are designed to support. From high-precision processes to complex experimental protocols, our solutions are engineered to meet the evolving needs of modern research and development.  - [Contact Us](https://www.scienion.com/contact-us/): Send us a message Contact Us Let us know how we can help Product Information ‎ ‎ ‎‎ ‎Customer Support‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎General Inquiries‎ ‎ ‎ ‎ Precision Microdispensing Single-cell and 3D Cell models First Name Last Name Email Phone Company Name Job Title Country Afghanistan Albania Algeria Andorra Angola Antigua & Deps Argentina Armenia Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bhutan Bolivia Bosnia Herzegovina Botswana Brazil Brunei Bulgaria Burkina Burundi Cambodia Cameroon Canada Cape Verde Central African Rep Chad Chile China Colombia Comoros Congo Congo {Democratic Rep} Costa Rica Croatia Cuba Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic East Timor Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Fiji Finland France Gabon Gambia Georgia Germany Ghana Greece Grenada Guatemala Guinea Guinea-Bissau Guyana Haiti Honduras Hungary Iceland India Indonesia Iran Iraq Ireland {Republic} Israel Italy Ivory Coast Jamaica Japan Jordan Kazakhstan Kenya Kiribati Korea North Korea South Kosovo Kuwait Kyrgyzstan Laos Latvia Lebanon Lesotho Liberia Libya Liechtenstein Lithuania Luxembourg Macedonia Madagascar Malawi Malaysia Maldives Mali Malta Marshall Islands Mauritania Mauritius Mexico Micronesia Moldova Monaco Mongolia Montenegro Morocco Mozambique Myanmar, {Burma} Namibia Nauru Nepal Netherlands New Zealand Nicaragua Niger Nigeria Norway Oman Pakistan Palau Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Qatar Romania Russian Federation Rwanda St Kitts & Nevis St Lucia Saint Vincent & the Grenadines Samoa San Marino Sao Tome & Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Slovakia Slovenia Solomon Islands Somalia South Africa South Sudan Spain Sri Lanka Sudan Suriname Swaziland Sweden Switzerland Syria Taiwan Tajikistan Tanzania Thailand Togo Tonga Trinidad & Tobago Tunisia Turkey Turkmenistan Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Vatican City Venezuela Vietnam Yemen Zambia Zimbabwe Message BICO Group AB is the controller for processing your personal data. By submitting, you acknowledge that we process your data based on our legitimate interest in providing relevant content and updates from companies within the BICO Group. Your information may be shared within the group to ensure you receive materials and invitations aligned with your interests. For further details on how we process your data and your rights, please review our Privacy Policy. Submit Precision Microdispensing Single-cell and 3D Cell models - [Connect with an Expert](https://www.scienion.com/connect-expert/): CONTACT US Connect with an Expert What are you interested in? Precision Microdispensing Single-cell and 3D Cell models - [The Company](https://www.scienion.com/company/): SCIENION, a spin-off from the Max Planck Institute, has been a leader in precision microdispensing since 2001. In 2016, Cellenion was founded as a subsidiary to bring that expertise into the world of single-cell and 3D biology.  - [Customer Service](https://www.scienion.com/customer-service/): GSS is the service backbone of all SCIENION and Cellenion platforms. Certified to ISO 9001 standards, our global team delivers preventive maintenance, calibration, remote troubleshooting, and application support designed to keep your instruments performing at factory standards. With local teams in Europe, Asia, and the Americas, we ensure rapid response times and transparent, traceable service; because consistent performance isn’t optional. - [sciCONSUMABLES – DO NOT USE](https://www.scienion.com/sciconsumables/): SCIENION offers innovative, complete and flexible solutions for multiplex assay development. The consumable portfolio covers all applications and includes SCIENION’s proprietary Piezo Dispense Capillaries (PDC), a range of dispensing buffers (sciBUFFERS), surface treated microplates (sciPLATES), functionalized glass slides (sciCHIPS) and microwell chips dedicated to single cell proteomics (proteoCHIPs). - [Important Legal Information](https://www.scienion.com/legal/): Important Legal Information ElektroG Compliance ElectroG Compliance Document - [Imprint, Legal Notes & Disclaimer](https://www.scienion.com/imprint/): This website is hosted by:SCIENION GmbHWagner-Régeny-Straße 1512489 Berlin, Germany - [Terms & Conditions](https://www.scienion.com/terms-conditions/): Please refer to BICO Group's General Terms and Conditions of Sale. - [Contract Print Services](https://www.scienion.com/contract-services/cps/): When you need high-quality printing for microarrays, biosensors, or diagnostic cartridges without investing in new infrastructure, SCIENION Contract Print Services (CPS) deliver ISO 9001-certified batch production using our sciFLEXARRAYER precision microdispensing technology. From pilot series to medium-size batches, we ensure reproducible results, full traceability, and the same precision that powers SCIENION instruments worldwide.  - [Contract Development Services](https://www.scienion.com/contract-services/cds/): Whether you’re developing a new diagnostic array, building on results from a Contract Application Service feasibility study, optimizing a microfluidic cartridge, or building a single-cell assay, Our Contract Development Services (CDS) provide the expertise and infrastructure to turn ideas into validated, automated workflows. Our specialists optimize parameters, materials, and volumes for precision, reproducibility, and scalability across both microdispensing and single-cell applications.  - [Contract Manufacturing Services](https://www.scienion.com/contract-services/cms/): For customers seeking secure, high-quality production at industrial scale, SCIENION Contract Manufacturing Services (CMS) provide fully traceable, ISO 9001-certified manufacturing using sciFLEXARRAYER precision microdispensing systems. Acting as your primary or secondary manufacturing site, we ensure reproducibility, compliance, and seamless supply across every batch.  - [Videos](https://www.scienion.com/resource-hub/videos/): Videos Back to Resource Hub Customers spotlights Precision Microdispensing Products & Technology Single cell and 3D models All - [Webinars](https://www.scienion.com/resource-hub/webinars/): We are deeply committed to providing insightful, informative, and educational content that advances understanding in the fields of precision dispensing, as well as single-cell, spheroid, and organoid isolation. - [Get a Quote](https://www.scienion.com/get-a-quote/): CONTACT US Get a Quote What are you interested in? Precision Microdispensing Single-cell and 3D Cell models - [Careers](https://www.scienion.com/company/careers/): As an equal opportunity employer, we do more than accept difference. We celebrate diversity, we support employees from a wide range of backgrounds, and we benefit from the added creativity and richness that these differences bring to our offices and community. We pride ourselves on being a collaborative environment where everyone’s talents and opinions contribute to the greater good and are always recognized. - [Publications](https://www.scienion.com/resource-hub/publications/): A low – cost strategy for manufacturing molecularly double-barcoded DNA arrays, enabling large – scale spatially resolved transcriptomic studies, is introduced. - [Brochures](https://www.scienion.com/resource-hub/brochures/): Brochures & Flyers Back to Resource Hub ALL INSTRUMENTS CONSUMABLES GENERAL ALL BROCHURES & FLYERS GO GO GO GO GO GO GO GO GO GO GO GO GO GO GO GO PRECISION DISPENSING INSTRUMENTS GO GO GO GO SINGLE CELL, SPHEROID & ORGANOID ISOLATION INSTRUMENTS ​ GO GO GO GO GO GO GO sciCONSUMABLES GO GO GO GO proteoCHIP GO GO GO GENERAL BROCHURES & FLYERS GO GO GO GO ALL BROCHURES & FLYERS PRECISION DISPENSING INSTRUMENTS SINGLE CELL, SPHEROID & ORGANOID ISOLATION INSTRUMENTS ​ sciCONSUMABLES proteoCHIP GENERAL BROCHURES & FLYERS - [Events](https://www.scienion.com/resource-hub/events/): Please stay tuned for updates on our upcoming events planned for 2026. - [Resources](https://www.scienion.com/resource-hub/): Resource Hub Reach out Contact Us APPLICATION & TECHNICAL NOTES → BLOG → WEBINARS → PUBLICATIONS → BROCHURES & FLYERS → VIDEOS → EVENTS → BROCHURES & FLYERS See All Application and Technical Notes See All WEBINARS See All VIDEOS See All BLOGS See All - [Contract Application Services](https://www.scienion.com/contract-services/cas/): Validate early concepts with SCIENION Contract Application Services (CAS). Our specialists help you test materials, evaluate printability, and generate reliable proof-of-concept data on SCIENION and Cellenion instruments. Accelerate your innovation with expert guidance, reproducible results, and a clear path toward development and manufacturing.  - [Products](https://www.scienion.com/products/): At SCIENION, we deliver cutting-edge, non-contact microdispensing instruments and consumables designed for unmatched accuracy, reproducibility, and automation, from research to high-throughput manufacturing. With over two decades of proven expertise, our sciFLEXARRAYER systems are trusted by diagnostics manufacturers, biosensor developers, and microarray producers worldwide. - [Applications](https://www.scienion.com/applications/): With over two decades of experience, SCIENION delivers trusted microdispensing platforms for applications ranging from early research to high-throughput manufacturing. Our technology powers critical workflows in diagnostics, microarrays, biosensors, and lateral flow production, combining accuracy, versatility, and unmatched reliability in every drop. - [Contract Services](https://www.scienion.com/contract-services/): Whether you're exploring new concepts or scaling manufacturing, our Contract Services support your journey, from feasibility to full production. Leveraging over 20 years of expertise in precision microdispensing and automation, we offer tailored services across SCIENION and Cellenion platforms. - [Home](https://www.scienion.com/): GO - [Privacy Policy](https://www.scienion.com/privacy-policy/): SCIENION is pleased that you have decided to visit our website and are interested in our company and products. We treat the protection of your personal data seriously and strive to ensure that you feel secure and comfortable when visiting our Internet pages. ## Application Technical Notes - [Single Pancreatic Organoid Proteomics Study](https://www.scienion.com/application-notes/single-pancreatic-organoid-proteomics-study/) - [Combining GrowDex and spheroONE for automated and highly reproducible 3D cell culture workflows](https://www.scienion.com/application-notes/combining-growdex-and-spheroone-for-optimal-spheroids-outgrowth/): AppNote 34 - UPM Biomedicals - Combining GrowDex and spheroONE - [Preparation of HepaRG spheroid assay-ready plates using spheroONE](https://www.scienion.com/application-notes/preparation-of-heparg-spheroid-assay-ready-plates-using-spheroone/): AppNote 33 - Biopredic - Preparation of HepaRG spheroid assay-ready plates using spheroONE - [High Throughput generation of bacterial isolate libraries using direct liquid cultivation with cellenONE](https://www.scienion.com/application-notes/2865-2/): AppNote 31 - High Throughput generation of bacterial isolate libraries using direct liquid cultivation with cellenONE - [Cardiomyocyte isolation using Cellenion’s cellenONE instrument](https://www.scienion.com/application-notes/cardiomyocyte-isolation-using-cellenions-cellenone-instrument/): AppNote 28 - Cedars-Sinai - Cardiomyocyte isolation using Cellenion’s cellenONE instrument - [Pushing the boundaries for robust and high-throughput single cell proteomics](https://www.scienion.com/application-notes/pushing-the-boundaries-for-robust-and-high-throughput-single-cell-proteomics/): AppNote 27 - EvoSep - Pushing the boundaries for robust and high-throughput single cell proteomics - [Automated 3D spheroids sorting, isolation and dispense](https://www.scienion.com/application-notes/automated-3d-spheroids-sorting-isolation-and-dispense/): AppNote 26 - Automated 3D spheroids sorting, isolation and dispense - [Combining cellenONE and timsTOF SCP for easy and sensitive, end-to-end label-free single cell proteomics workflows](https://www.scienion.com/application-notes/combining-cellenone-and-timstof-scp-for-easy-and-sensitive-end-to-end-label-free-single-cell-proteomics-workflows/): AppNote 25 - Bruker - Combining cellenONE and timsTOF SCP for easy and sensitive, end-to-end label-free single cell proteomics workflows - [cellenONE as automated single cell seeding platform for hiPSC subcloning](https://www.scienion.com/application-notes/cellenone-as-automated-single-cell-seeding-platform-for-hipsc-subcloning/): AppNote 22 - Charite Berlin - cellenONE as automated single cell seeding platform for hiPSC subcloning - [Multiplexed single cell proteomics sample preparation using the proteoCHIP](https://www.scienion.com/application-notes/multiplexed-single-cell-proteomics-sample-preparation-using-the-proteochip/): AppNote 20 - IMP Vienna - Multiplexed single cell proteomics sample preparation using the proteoCHIP - [Automated single cell isolation from multiple samples with cellenONE](https://www.scienion.com/application-notes/2858-2/): AppNote 19 - Automated single cell isolation from multiple samples with cellenONE - [Automated process for mother cell cloning and subsequent daughter cells isolation with the cellenONE](https://www.scienion.com/application-notes/automated-process-for-mother-cell-cloning-and-subsequent-daughter-cells-isolation-with-the-cellenone/): AppNote 16 - ENS - Automated process for mother cell cloning and subsequent daughter cells isolation with the cellenONE - [SCoPE2-MS for single cell proteomics sample preparation using cellenONE](https://www.scienion.com/application-notes/scope2-ms-for-single-cell-proteomics-sample-preparation-using-cellenone/): AppNote 13 - IMP Vienna - SCoPE2-MS for single cell proteomics sample preparation using cellenONE - [Rarecyte – Accurate and precise spike-in method for CTC validation studies with cellenONE®](https://www.scienion.com/application-notes/rarecyte-accurate-and-precise-spike-in-method-for-ctc-validation-studies-with-cellenone/): AppNote 11 - Rarecyte - Accurate and precise spike-in method for CTC validation studies with cellenONE® - [cellenONE sterile condition operation](https://www.scienion.com/application-notes/cellenone-sterile-condition-operation/): AppNote 06 - cellenONE sterile condition operation - [DLP+: Scaling Whole-Genome Sequencing to 50,000 single cells using cellenONE](https://www.scienion.com/application-notes/dlp-scaling-whole-genome-sequencing-to-50000-single-cells-using-cellenone/): AppNote 05 - University of British Columbia (DLPplus method) - Scaling Whole-Genome Sequencing to 50,000 single cells using cellenONE - [Unparalleled clonal outgrowth achieved in 96-,384- and-1536- microtiter plates](https://www.scienion.com/application-notes/unparalleled-clonal-outgrowth-achieved-in-96-384-and-1536-microtiter-plates/): AppNote 03 - Unparalleled clonal outgrowth achieved in 96-,384- and-1536- microtiter plates - [Single bead isolation made easy](https://www.scienion.com/application-notes/single-bead-isolation-made-easy/): AppNote 02 - PolyAn - Single bead isolation made easy - [MACSQuant TYTO and cellenONE for development of monoclonal cell lines](https://www.scienion.com/application-notes/macsquant-tyto-and-cellenone-for-development-of-monoclonal-cell-lines/): AppNote 01bis - MACSQuant TYTO and cellenONE for development of monoclonal cell lines - [sciPULSE ULTRA LOW VOLUME – Dispensing of small droplets in the range of 18 – 180 pL](https://www.scienion.com/application-notes/scipulse-ultra-low-volume-dispensing-of-small-droplets-in-the-range-of-18-180-pl/) - [Making spatial transcriptomics accessible: Cost-effective manufacturing of DNA arrays using double-barcoded probes and the sciFLEXARRAYER S3 precision microdispenser](https://www.scienion.com/application-notes/making-spatial-transcriptomics-accessible-cost-effective-manufacturing-of-dna-arrays-using-double-barcoded-probes-and-the-sciflexarrayer-s3-precision-microdispenser/) - [Surface functionalization of Evonetix’s microchip platform for DNA synthesis](https://www.scienion.com/application-notes/surface-functionalization-of-evonetixs-microchip-platform-for-dna-synthesis/) - [The next generation of LFA – Multiplexing on Unisart StructSure® membranes](https://www.scienion.com/application-notes/the-next-generation-of-lfa-multiplexing-on-unisart-structsure-membranes/) - [Rapid and multi-analyte diagnostic microarrays](https://www.scienion.com/application-notes/rapid-and-multi-analyte-diagnostic-microarrays/) - [Development of a new and sensitive multi-analyte lateral flow immunoassay for the verification of three inflammation markers](https://www.scienion.com/application-notes/development-of-a-new-and-sensitive-multi-analyte-lateral-flow-immunoassay-for-the-verification-of-three-inflammation-markers/) - [RAPCARL: A rapid Carbohydrate Array Lateral Flow Test Technology for simultaneous detection of thirteen different species from S. pneumoniae, N. meningitides and H. influenzae](https://www.scienion.com/application-notes/rapcarl-a-rapid-carbohydrate-array-lateral-flow-test-technology-for-simultaneous-detection-of-thirteen-different-species-from-s-pneumoniae-n-meningitides-and-h-influenzae/) - [Multiplexed ELISA of cardiovascular disease biomarkers in 96 well plate](https://www.scienion.com/application-notes/multiplexed-elisa-of-cardiovascular-disease-biomarkers-in-96-well-plate/) - [Miniaturization and multiplexing of a lateral flow immunoassay for the detection of Rotavirus, Coronavirus, Escherichia coli F5 (K99) and Cryptosporidium in calf faeces](https://www.scienion.com/application-notes/miniaturization-and-multiplexing-of-a-lateral-flow-immunoassay-for-the-detection-of-rotavirus-coronavirus-escherichia-coli-f5-k99-and-cryptosporidium-in-calf-faeces/) - [Protein microarrays on unmodified polymer supports using sciPOLY3D](https://www.scienion.com/application-notes/protein-microarrays-on-unmodified-polymer-supports-using-scipoly3d/) - [DNA microarrays using sciPOLY3D – Comparison of sciCHIP COP and epoxy-functionalized supports](https://www.scienion.com/application-notes/dna-microarrays-using-scipoly3d-comparison-of-scichip-cop-and-epoxy-functionalized-supports/) ## Applications - [Microfluidics](https://www.scienion.com/applications/microfluidics/): Microfluidics is the science and technology of controlling and analyzing very small volumes of liquid within microscale channels, which are often less than a millimeter in width. These channels are typically fabricated in materials such as glass, silicon, or polymer substrates and are used to transport, mix, separate, or analyze fluids with high precision. The concept, widely referred to as “lab-on-a-chip,” is an application of microfluidics and has transformed experimental design by condensing entire laboratory workflows into miniaturized and highly efficient systems.  - [Microarrays and Biosensors](https://www.scienion.com/applications/biosensors/): Microarrays and biosensors are two cornerstone technologies in modern diagnostics and life sciences, enabling the simultaneous detection of multiple biological targets from a single, minimal-volume sample. Microarrays are structured matrices of immobilized biomolecules (DNA, RNA, proteins, or antibodies) that capture and analyze specific analytes in parallel. They are used for applications such as biomarker discovery, disease diagnostics, drug response profiling, and personalized medicine. Biosensors, on the other hand, convert biological recognition events into measurable physical or chemical signals. They take many forms, electrochemical, optical, or mass-sensitive, and are increasingly used in point-of-care diagnostics, environmental testing, and real-time health monitoring. - [Lateral Flow](https://www.scienion.com/applications/lateral-flow/): Lateral flow is a rapid, simple, and low-cost diagnostic technology widely used for point-of-care testing. It works by allowing a liquid sample to migrate along a membrane strip, where immobilized reagents capture target molecules, producing a visible result typically within minutes. Many are familiar with lateral flow through common applications, such as pregnancy testing and COVID-19 rapid antigen testing.  - [Microneedle Drug Delivery](https://www.scienion.com/applications/microneedles/): The stratum corneum, just 20 µm thick, represents one of medicine's most formidable barriers. Microneedles solve this challenge, creating painless pathways through the skin's outer layer to deliver vaccines, biologics, and small molecules directly into the vascularized dermis and epidermis. With 60-95% pain reduction compared to hypodermic injections and the convenience of self-administration, microneedle patches are transforming drug delivery for everything from insulin and immunotherapy to cosmetic applications. - [Single Cell Proteomics](https://www.scienion.com/applications/single-cell-proteomics/): Single-cell proteomics (SCP) is an emerging field that uses mass spectrometry to measure thousands of proteins in individual cells. Unlike single-cell transcriptomics, which reflects potential activity, SCP reveals the actual molecules driving cell function, signalling, and disease mechanisms. This makes it a powerful complement for precision medicine, helping researchers identify rare pathogenic cells, track drug responses at single-cell resolution, and uncover new therapeutic targets. ## Customer Spotlights - [SCIFLEXARRAYER](https://www.scienion.com/customer-spotlights/sciflexarrayer-3/) - [SCIFLEXARRAYER](https://www.scienion.com/customer-spotlights/sciflexarrayer-2/) - [SCIFLEXARRAYER](https://www.scienion.com/customer-spotlights/sciflexarrayer/) ## Jobs - [Customer Success Manager](https://www.scienion.com/jobs/customer-success-manager/) - [Team Lead](https://www.scienion.com/jobs/team-lead/) - [Product Manager](https://www.scienion.com/jobs/product-manager/) - [Full Stack Developer](https://www.scienion.com/jobs/full-stack-developer/) - [Applications Scientist](https://www.scienion.com/jobs/applications-scientist/) ## Products - [cellenONE X1 Neo](https://www.scienion.com/products/cellenone-single-cell-dispensers/cellenone-x1-neo/): NEO is the optimal tool for the preparation of single cell omics samples, thanks to end-to-end automated workflows and optimized environmental controls allowing on-deck incubations. And because it shares the core technologies of all cellenONE single cell dispensers, it is virtually compatible with any other single cell applications. - [Buffers & Reagents](https://www.scienion.com/products/sciconsumables/buffers-reagents/): THE REAGENTS FOR ALL STEPS OF YOUR DNA & PROTEIN MICROARRAY WORKFLOWS - [Dispensing Capillaries](https://www.scienion.com/products/sciconsumables/pdcs/): At the heart of SCIENION’s systems lie two complementary dispensing technologies, sciDROP PICO and sciDROP NANO, each powered by its own family of precision capillaries. Piezo Dispense Capillaries (PDC) enable picoliter-scale, pulse-driven droplet generation, while Nano Dispense Capillaries (NDC) support nanoliter-to-microliter jetting through electromagnetic micro-valve control. Together, they form the foundation of our reproducible, non-contact dispensing ecosystem.  - [sciPLATES and CHIPS](https://www.scienion.com/products/sciconsumables/plates-chips/): SURFACE TREATED MICROPLATES OPTIMIZED FOR MINIATURIZED ASSAYS - [Custom Solutions](https://www.scienion.com/products/custom-solutions/): Every assay, substrate, and process is unique, and so are your requirements. Through SCIENION and Cellenion Custom Solutions, we design, adapt, and integrate precision dispensing technologies around your application. Whether you need a modified instrument, custom holders for specialized targets, additional dispensing channels, or full in-line automation, our engineering team transforms your specifications into validated, production-ready systems. - [sciCONSUMABLES](https://www.scienion.com/products/sciconsumables/): SCIENION offers innovative, complete and flexible solutions for multiplex assay development. The consumable portfolio covers all applications and includes SCIENION’s proprietary Piezo Dispense Capillaries (PDC), a range of dispensing buffers (sciBUFFERS), surface treated microplates (sciPLEXPLATES), functionalized glass slides (sciCHIPS) and microwell chips dedicated to single cell proteomics (proteoCHIPs). - [sciFLEXARRAYER S100](https://www.scienion.com/products/sciflexarrayer/s100/): The sciFLEXARRAYER S100 is our fully customizable, integration-ready platform for ultra-high-throughput manufacturing. Configure up to twelve channels, and combine S100 portals to inline stations and custom fixtures; connect vision, robotics, or conveyors. The S100 uses the same dispensing technologies (PICO/NANO) and vision-based drop control as the rest of the family, but in a cabinetized architecture designed for continuous operation, rapid serviceability and validation. When your roadmap calls for scaling to true production lines, S100 turns precision microdispensing into a robust, automated process. - [sciFLEXARRAYER SX](https://www.scienion.com/products/sciflexarrayer/sx/): Designed for high-throughput batch production, the sciFLEXARRAYER SX delivers consistent results across large runs of slides or plates. Its robust mechanics, multi-channel dispensing and automation-friendly layout enable long, unattended sequences with tight process control and excellent batch-to-batch reproducibility. Whether you’re manufacturing multiplex assays, microarrays or lateral-flow components, SX provides the throughput you need without compromising accuracy. Same PICO/NANO compatibility, same software, just scaled for production environments, including cleanroom use. - [sciFLEXARRAYER S12](https://www.scienion.com/products/sciflexarrayer/s12/): The sciFLEXARRAYER S12 is a medium-batch microdispensing workhorse for labs moving beyond prototyping. With larger target capacity (up to 12 standard microplates) and up to eight channels, S12 accelerates screening campaigns and small-scale manufacturing while maintaining the drop control, positional accuracy and reproducibility the platform is known for. It supports picoliter dispensing as standard and nanoliter as a custom option, plus application-dedicated software packages that streamline routine runs. If S3 proves the concept, S12 helps you industrialize it, efficiently, repeatably, and without changing technology. - [sciFLEXARRAYER S3](https://www.scienion.com/products/sciflexarrayer/s3/): Access high-end microdispensing technology without overcommitment. The sciFLEXARRAYER S3 is where focused R&D begins: compact, capable, and built for teams who want to prototype with the same precision technology used in advanced manufacturing at low-risk costs. In its Catalyst configuration, it offers full access to reliable picoliter and nanoliter dispensing, ready to support applications like biochips, microarrays, biosensors, or lateral-flow tests. Best of all, it’s built to grow with you: add modules, switch tools, or script your own workflows as your projects evolve. You don’t need to compromise now or re-invest later. Start right, and stay on track. - [cellenONE Single Cell Dispensers](https://www.scienion.com/products/cellenone-single-cell-dispensers/): Combining ultra-precise image-based single‑cell isolation with gentle droplet dispensing, the cellenONE platforms deliver 100% accuracy, exceptional viability, and compatibility with cells sized 0.5–80 µm. They empower breakthroughs in various cutting-edge applications, such as single cell omics, spatial proteomics, cell engineering and high-throughput bioprocessing. Available in multiple versions to fit diverse application needs, from R&D to GMP environments. - [sciFLEXARRAYER Precision Dispensers](https://www.scienion.com/products/sciflexarrayer/): sciFLEXARRAYER is a range of high-precision, non-contact dispensing systems designed for the accurate spotting of liquids from 10 pL to 5,000 nL. Widely used in diagnostics and life sciences, these platforms enable the development and manufacturing of biochips, biosensors, and other analytical tools, delivering exceptional reproducibility with minimal sample waste. - [ProteoChip 12*16](https://www.scienion.com/products/proteochip-1216/): The proteoCHIP 12*16 has a microscope slide footprint, allowing novel miniaturized single cell proteomics applications in nanoliter-scale volumes.Each proteoCHIP contains 12 arrays (pools) of 16 wells each, enabling peptide labelling with TMTpro (either 1At CELLINK, we are proud of our many nationalities spanning 5 offices around the globe. Each office’s culture influencing the others’ and our 3 core values: Passion, Persistence and Inspiration. On the daily, our team is delivering on our vision to create the future of health. ## Videos - [spheroONE page Effect of CPM over isolated spheroids](https://www.scienion.com/videos/spheroone-page-effect-of-cpm-over-isolated-spheroids/) - [sciFLEXARRAYER S100 High-throughput microarray printer](https://www.scienion.com/videos/sciflexarrayer-s100-high-throughput-microarray-printer/) - [Mbio Diagnostics and its LightDeck technology, using sciFLEXARRAYER](https://www.scienion.com/videos/mbio-diagnostics-and-its-lightdeck-technology-using-sciflexarrayer/) - [Multiplex Assay Development Services. Multiplexing in planar and suspension format](https://www.scienion.com/videos/multiplex-assay-development-services-multiplexing-in-planar-and-suspension-format/) - [Microarray spotter. Picoliter and nanoliter dispensing. Animation](https://www.scienion.com/videos/microarray-spotter-picoliter-and-nanoliter-dispensing-animation/) - [Picoliter and nanoliter dispenser. Drop-on-demand dispensing](https://www.scienion.com/videos/picoliter-and-nanoliter-dispenser-drop-on-demand-dispensing/) - [Tuomas Tenkanen, CEO MOBIDIAG, talking about SCIENION](https://www.scienion.com/videos/tuomas-tenkanen-ceo-mobidiag-talking-about-scienion/) - [Dr. Marquette, at CNRS and 3d.FAB platform, talks about SCIENION](https://www.scienion.com/videos/dr-marquette-at-cnrs-and-3d-fab-platform-talks-about-scienion/) - [Automated manufacturing of multiplex diagnostic devices](https://www.scienion.com/videos/automated-manufacturing-of-multiplex-diagnostic-devices/) - [Manufacturing of innovative diagnostics – MEDICA 2022 highlights](https://www.scienion.com/videos/manufacturing-of-innovative-diagnostics-medica-2022-highlights/) - [N-ABLE: a new standard for liquid handling laboratory automation / SLAS 2023](https://www.scienion.com/videos/n-able-a-new-standard-for-liquid-handling-laboratory-automation-slas-2023/) - [IVD contract development and manufacturing](https://www.scienion.com/videos/ivd-contract-development-and-manufacturing/) - [SCIENION sciDROP PICO technology in images](https://www.scienion.com/videos/scienion-scidrop-pico-technology-in-images/) - [SCIENION sciFLEXARRAYER NANO A/D](https://www.scienion.com/videos/scienion-sciflexarrayer-nano-a-d/) - [Multiplexing with Unisart StructSure Membranes – Sartorius & SCIENION joint Webinar](https://www.scienion.com/videos/multiplexing-with-unisart-structsure-membranes-sartorius-scienion-joint-webinar/) - [Roll-to-roll nanoimprinting. SCIENION’s precision dispensing](https://www.scienion.com/videos/roll-to-roll-nanoimprinting-scienions-precision-dispensing/) - [Swing high-throughput microarray spotter. Picoliter and nanoliter dispensing](https://www.scienion.com/videos/swing-high-throughput-microarray-spotter-picoliter-and-nanoliter-dispensing/) - [Dr. Nikolas Daskalakis (BioNano Consulting) to develop medical diagnostic devices with SCIENION](https://www.scienion.com/videos/dr-nikolas-daskalakis-bionano-consulting-to-develop-medical-diagnostic-devices-with-scienion/) - [Prof. Cass talks about his research and how they use SCIENION technology to develop new biosensors](https://www.scienion.com/videos/prof-cass-talks-about-his-research-and-how-they-use-scienion-technology-to-develop-new-biosensors/) - [Precision dispensing of picoliters and nanoliters with sciFLEXARRAYER product line](https://www.scienion.com/videos/precision-dispensing-of-picoliters-and-nanoliters-with-sciflexarrayer-product-line/) - [Microneedle coating. Drop coating of microneedles. Drug delivery with microneedles.](https://www.scienion.com/videos/microneedle-coating-drop-coating-of-microneedles-drug-delivery-with-microneedles/) - [Orphidia enable large sets of human biomarkers to be monitored simultaneously thanks to SCIENION technology](https://www.scienion.com/videos/orphidia-enable-large-sets-of-human-biomarkers-to-be-monitored-simultaneously-thanks-to-scienion-technology/) - [Wageningen University: SCIENION-enabled Lateral Flow diagnostics](https://www.scienion.com/videos/wageningen-university-scienion-enabled-lateral-flow-diagnostics/) - [Microarray spotting onto membranes. Multiplex lateral flow. Picoliter and nanoliter dispensing](https://www.scienion.com/videos/microarray-spotting-onto-membranes-multiplex-lateral-flow-picoliter-and-nanoliter-dispensing/) - [Biosensor printing by sciFLEXARRAYER](https://www.scienion.com/videos/biosensor-printing-by-sciflexarrayer/) - [MicroAQUA: Innovative Aquatic Biosensors, printed with SCIENION systems](https://www.scienion.com/videos/microaqua-innovative-aquatic-biosensors-printed-with-scienion-systems/) - [Unisensor manufactures biosticks using sciFLEXARRAYER technology](https://www.scienion.com/videos/unisensor-manufactures-biosticks-using-sciflexarrayer-technology/) - [Mecwins sandwich immunoassays, powered by SCIENION](https://www.scienion.com/videos/mecwins-sandwich-immunoassays-powered-by-scienion/) - [Genalyte and its silicon photonic chip produced with SCIENION technology](https://www.scienion.com/videos/genalyte-and-its-silicon-photonic-chip-produced-with-scienion-technology/) - [How ImmunArray use sciFLEXARRAYER technology to print their multiplexed Lupus diagnostic tests](https://www.scienion.com/videos/how-immunarray-use-sciflexarrayer-technology-to-print-their-multiplexed-lupus-diagnostic-tests/) - [Stanford University Prints Sensitive Chip to Detect Cancer Proteins Using sciFLEXARRAYER](https://www.scienion.com/videos/stanford-university-prints-sensitive-chip-to-detect-cancer-proteins-using-sciflexarrayer/) - [Intuitive Biosciences and its AIM offering multiplex immunoassay solutions](https://www.scienion.com/videos/intuitive-biosciences-and-its-aim-offering-multiplex-immunoassay-solutions/) - [QuantuMDx & SCIENION partner to develop highly multiplexed nanowire array](https://www.scienion.com/videos/quantumdx-scienion-partner-to-develop-highly-multiplexed-nanowire-array/) - [GENOMICA & SCIENION, pioneering in vitro molecular diagnostics](https://www.scienion.com/videos/genomica-scienion-pioneering-in-vitr-molecular-diagnostics/) - [microLIFE & cellenONE – Launch Video](https://www.scienion.com/videos/microlife-cellenone-launch-video/) - [microLIFE Teaser](https://www.scienion.com/videos/microlife-teaser/) - [proteoCHIP LF-48 – Workflow](https://www.scienion.com/videos/proteochip-lf-48-workflow/) - [cellenONEHT](https://www.scienion.com/videos/cellenoneht/) - [spheroONE: Automated sorting and isolation of single spheroids and organoids](https://www.scienion.com/videos/spheroone-automated-sorting-and-isolation-of-single-spheroids-and-organoids/) - [proteoCHIP: Automated & miniaturized single cell proteomics sample preparation](https://www.scienion.com/videos/proteochip-automated-miniaturized-single-cell-proteomics-sample-preparation/) - [cellenONE: Single Cell Isolation & Nanoliter Dispenser for Single Cell Proteomics Sample Preparation](https://www.scienion.com/videos/cellenone-single-cell-isolation-nanoliter-dispenser-for-single-cell-proteomics-sample-preparation/) - [cellenONE Single Cell Isolation & Dispensing Technology from Cellenion](https://www.scienion.com/videos/cellenone-single-cell-isolation-dispensing-technology-from-cellenion/) - [cellenONE X1 dispensing in 96 well plate](https://www.scienion.com/videos/cellenone-x1-dispensing-in-96-well-plate/) - [cellenONE X1 featured at SLAS 2018](https://www.scienion.com/videos/cellenone-x1-featured-at-slas-2018/) - [PC3 cells isolated with cellenONE X1](https://www.scienion.com/videos/pc3-cells-isolated-with-cellenone-x1/) - [Isolating beads with fluorescence mode. cellenion F1.4 at QDJ](https://www.scienion.com/videos/isolating-beads-with-fluorescence-mode-cellenion-f1-4-at-qdj/) - [cellenONE Software and Deck view](https://www.scienion.com/videos/cellenone-software-and-deck-view/) - [cellenONE Workshop Interview Series – Dr. Zilu Ye](https://www.scienion.com/videos/cellenone-workshop-interview-series-dr-zilu-ye/) - [cellenONE Workshop Interview Series – Dr. Ljiljana Paša-Tolić](https://www.scienion.com/videos/cellenone-workshop-interview-series-dr-ljiljana-pasa-tolic/) - [cellenONE Workshop Interview Series – Dr. Maximilian Mossner](https://www.scienion.com/videos/cellenone-workshop-interview-series-dr-maximilian-mossner/) ## Webinars - [Beyond Off-The-Shelf: Custom Solutions for Microdispensing Applications](https://www.scienion.com/webinars/beyond-off-the-shelf-custom-solutions-for-microdispensing-applications/): Precision dispensing projects often require more than standard off-the-shelf instrumentation or procedures. Whether it's integrating modules into an existing microdispensing production line, adapting to specific environmental needs, or implementing custom software, these challenges need tailored solutions. Such solutions rely on validated instrumentation and production processes, and most importantly, expert collaboration and partnership. - [The Histone Code, One Single Cell at a Time](https://www.scienion.com/webinars/the-histone-code-one-single-cell-at-a-time/): Recent advances in epigenetics have revealed the complexity of the “histone code,” yet most measurements still rely on bulk analyses that obscure cell-to-cell variation. What if the most important regulatory signals are hidden in this averaging? - [Drug response profiling of primary colorectal tumor models using spheroONE and Pu·MA System EC automated workflow](https://www.scienion.com/webinars/drug-response-profiling-of-primary-colorectal-tumor-models-using-spheroone-and-pu%c2%b7ma-system-ec-automated-workflow/): Learn about a novel automated workflow using the spheroONE and Pu.Ma System EC (Protein Fluidics) for drug response profiling of patient-derived tumor models. Primary tumoroids are sorted & dispensed into flowchips for drug testing using phenotypic assays. Automated compound incubation and viability staining lead to consistent reproducible high-quality data. - [FACS OFF! Autonomous and high-throughput Single Cell Cloning](https://www.scienion.com/webinars/webinar-facs-off-cellenion-biosero/): B-cell cloning is an industry standard method for reliable and reproducible production of monoclonal antibodies (mAb). A typical journey in mAb development involves B cells isolation prior to screening. For years, FACS has been the method of choice for semi-automated seeding of single cells into microwell plates. However, this method suffers from low throughput due to inherent difficulties to automate start up, calibration, sample/target exchange processes. Furthermore, FACS is labour-intensive as it requires continuous presence of skilled operator to monitor and troubleshoot the process. Hence, the need of an alternative approach that addresses the aforementioned shortcomings that are: throughput, clonability, and high operating costs. In this webinar, we present how cellenONE HT, an image-based single cell isolation platform, is fully automated using Green Button Go Scheduler so that it operates continuously without the need for an operator, effectively enabling 24/7 unattended single cell plating from one or multiple samples. - [Multiplexing with Unisart StructSure®️ Membranes Webinar](https://www.scienion.com/webinars/multiplexing-with-unisart-structsure%ef%b8%8f-membranes-webinar/): In recent years, multiplex lateral flow assays have become increasingly popular in disease management because they can rapidly analyze multiple parameters or biomarkers simultaneously. In this webinar, a complete solution including assay development with structured membranes, cassette use, and advanced LFA readout is showcased in a multiplex lateral flow test. The miniaturization of lines to spots using the dot-based dispensing technology from SCIENION GmbH in combination with the separation on the unique structured Unisart StructSure® membrane from Sartorius results in improved assay performance and reliability compared to the use of conventional lateral flow tests in line. - [spheroONE for the preparation of standardized HepaRG assay ready plates](https://www.scienion.com/webinars/spheroone-for-the-preparation-of-standardized-heparg-assay-ready-plates/): This work was realized in collaboration with Biopredic International, visit their website here: https://wepredic.com/en/ - [NextGen Omics UK 2022 – Recorded Presentation](https://www.scienion.com/webinars/francois-monjaret-phd-nextgen-omics-uk-2022-recorded-presentation/): Our former CSO presented in 2022 how cellenONE and its accessories can be used in single cell omics, from single cell genomics and transcriptomics, to single cell proteomics and multiomics. - [Single Cell Proteomics Day of the Italian Mass Spectrometry Society: cellenONE and proteoCHIP for robust single cell proteomics](https://www.scienion.com/webinars/david-hartlmayr-single-cell-proteomics-day-italian-mass-spectrometry-society/): singDiscover cellenONE, for end-to-end sample preparation for single cell proteomics, from single cell isolation to autosampling, for seamless, low-loss and robust SCP workflows. - [Cellenion product overview](https://www.scienion.com/webinars/single-cell-isolation-and-applications-spheroid-and-organoid-isolation-and-workflows/): In this Webinar performed in collaboration with Accela, our Scientist Steffen Cosson gave an overview of our products and technology, from cellenONE for single cell isolation and single cell omics sample preparation, to its younger sibling spheroONE, for the sorting and isolation of spheroids and organoids. - [Building Biology 3D Hybrid Symposium – spheroONE](https://www.scienion.com/webinars/bb3d-presentation-by-steffen-cosson-phd-spheroone/): Four years ago, our scientist Steffen Cosson presented the first results of what would become the spheroONE, our solution for 3D cell models sorting isolation. The spheroONE enables standardization of spheroids and organoids for drug testing, based on size, morphology and fluorescence. - [proteoCHIP Launch Dinner Presentation – ASMS 2021](https://www.scienion.com/webinars/proteochip-launch-dinner-presentation-by-anjali-seth-phd-claudia-ctortecka-asms-2021/): In 2021, we launched our very first single cell proteomcis consumable, the proteoCHIP. This session was recorded during the launch dinner at ASMS 2021: since then, tens of labs have adopted cellenONE and proteoCHIPs, for seamless and robust SCP workflows. - [ESCP2021 Recording – Introduction by Karl Mechtler](https://www.scienion.com/webinars/escp2021-recording-introduction-by-karl-mechtler/): This year’s ESCP2021 virtual event focused on recent advances in sample preparation to overcome limitations and push the boundaries in single-cell proteomics workflows. - [Single Cell Transcriptome Analyses of HepaRG™ Cells using cellenONE Technology](https://www.scienion.com/webinars/single-cell-transcriptome-analyses-of-heparg-cells-using-cellenone-technology/): Cellenion present here solutions for single-cell analyses of 3D cellular models. Cellenion has developed cellenONE, a unique system able to both isolate single-cell with high accuracy and dispense nanoliters of reagents allowing miniaturization of sample preparation for OMICs studies. The emergence of single-cell analyses has revolutionized Biology most notably in the field of Oncology. Making single-cell analyses affordable is critical to the deployment of these methods to other research fields. - [cellenONE, an open platform for Single Cell Isolation & Miniaturizing Library Preparation](https://www.scienion.com/webinars/webinar-cellenion-cellenone-for-single-cell-isolation-miniaturizing-library-preparation/): Dr Guilhem Tourniaire, managing director of Cellenion Lyon, offered in 2020 this overview of cellenONE usage for single cell isolation and single cell omics sample preparation.