Electron Microscopy

Nanoparticle Characterization

TEM and SEM measurements are commonly used methods for characterization of nanomaterials. Typically a single sample is applied onto an EM specimen holder or grid. Due to the fact that these grids have to be moved inside a vacuum chamber, the actual sample exchange may take several minutes depending on the EM instrument. Using a new loading technology, utilizing  picoliter  dispensing  to  print  arrays of up to 100 samples on one EM support, results in a significant increase in sample throughput while decreasing operational costs in EM measurements significantly.

Vizualization of Nanoscale Processes

Liquid cell transmission electron microscopy (LCTEM) provides a unique insight into the dynamics of nanomaterials in solution. Controlling the addition of multiple solutions to the liquid cell remains a key hurdle in our ability to increase throughput and to study processes dependent on solution mixing including chemical reactions. SCIENIONĀ“s piezo dispensing technique allows for mixing of multiple solutions directly within the viewing area. This technique permits deposition of 50 pL droplets of various aqueous solutions onto the liquid cell window, before assembly of the cell in a fully controlled manner.