Thank you for taking the time to fill out the SCIENION Newsletter Sign up. Your email will be included in our next campaign.
Advances in disease diagnostics now offer clinicians a staggering degree of accuracy. But access to results generally requires a well-equipped lab and a few weeks waiting time.
To overcome these limitations, British medical device developer QuantuMDx (QMDx) and SCIENION have partnered to take QMDx's highly multiplexed nanowire array to market. This biosensor is a component of QMDx's flagship product Q-POC™, a handheld molecular diagnostic device that will provide results in 20 minutes for a few pounds at the patient's side.
QuantuMDx is a life science tools and diagnostics company headquartered in Newcastle upon Tyne, UK with offices in the USA and Singapore. QuantuMDx’s mission is to improve and democratise global healthcare by developing transformative technologies that will enable rapid, accurate and affordable diagnostic testing in the community.
QuantuMDx is currently developing the Q-POC™ platform: a point-of-care, rapid, portable, molecular analyser to diagnose a range of diseases in under 20 minutes, depending on the complexity of the test, including tuberculosis, STIs and HPV. It will also serve as a companion medical device to optimise or monitor treatments such as Warfarin.
Scienion began supporting QuantuMDx in 2015, installing the sciFLEXARRAYER SX printer during their early research phase, to enable high throughput microarray production.
Since then, QMDx utilises SCIENION's proprietary ultra-low volume liquid handling technologies to transfer biological material onto QMDx's novel biosensor. Each nanowire in the array is printed with molecular probes; with hundreds of nanowires in each silicon biosensor chip, the multiplexing potential is massive.
The Wall Street Journal - Trading Stories - Transforming Global Health Diagnostics
“We have worked in partnership with the team at SCIENION who have supported our development of customised arrays – enabling us to print DNA to a range of substrates, such as plastic, glass or silicon, depending on the application. The tool offers accurate, precision printing, at speed. As the printer is scalable we’ll eventually be able to produce high volumes of microarrays when we start manufacturing and bring our molecular diagnostic assays to market.”
Q-POC™ differs from most conventional point-of-care diagnostic tools in that it analyses the DNA of pathogens rather than the proteins within the sample. The device depends on microfluidic technology , which essentially allows fluids to pass through different microscopic channels of different diameters.
Q-POC™ will initially be used to detect tuberculosis, with tests for other disease conditions added at a later date. The device has a built-in cell phone technology, enabling the test results to be geo-stamped and shared in real time, potentially opening the door to continuous monitoring of disease and antimicrobial resistance.
The companies' longstanding relationship was cemented with QMDx's purchase of SCIENION's sciFLEXARRAYER SX, and will continue to grow as the companies embark on a number of development projects to take the biosensor characterisation from R&D to mass manufacture.